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P-cadherin counteracts myosin II-B function: implications in melanoma progression

BACKGROUND: Malignant transformation of melanocytes is frequently attended by a switch in cadherin expression profile as shown for E- and N-cadherin. For P-cadherin, downregulation in metastasizing melanoma has been demonstrated, and over-expression of P-cadherin in melanoma cell lines has been show...

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Detalles Bibliográficos
Autores principales: Jacobs, Koen, Van Gele, Mireille, Forsyth, Ramses, Brochez, Lieve, Vanhoecke, Barbara, De Wever, Olivier, Bracke, Marc
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2949802/
https://www.ncbi.nlm.nih.gov/pubmed/20860798
http://dx.doi.org/10.1186/1476-4598-9-255