Tumour stromal cells derived from paediatric malignancies display MSC-like properties and impair NK cell cytotoxicity

BACKGROUND: Tumour growth and metastatic infiltration are favoured by several components of the tumour microenvironment. Bone marrow-derived multipotent mesenchymal stromal cells (MSC) are known to contribute to the tumour stroma. When isolated from healthy bone marrow, MSC exert potent antiprolifer...

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Detalles Bibliográficos
Autores principales: Johann, Pascal-David, Vaegler, Martin, Gieseke, Friederike, Mang, Philippa, Armeanu-Ebinger, Sorin, Kluba, Torsten, Handgretinger, Rupert, Müller, Ingo
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2949810/
https://www.ncbi.nlm.nih.gov/pubmed/20858262
http://dx.doi.org/10.1186/1471-2407-10-501

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2949810/
https://www.ncbi.nlm.nih.gov/pubmed/20858262
http://dx.doi.org/10.1186/1471-2407-10-501

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