A role for the histone deacetylase HDAC4 in the life-cycle of HIV-1-based vectors

HIV-1 integration is mediated by the HIV-1 integrase protein, which joins 3'-ends of viral DNA to host cell DNA. To complete the integration process, HIV-1 DNA has to be joined to host cell DNA also at the 5'-ends. This process is called post-integration repair (PIR). Integration and PIR i...

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Detalles Bibliográficos
Autores principales: Smith, Johanna A, Yeung, Jennifer, Kao, Gary D, Daniel, René
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2949839/
https://www.ncbi.nlm.nih.gov/pubmed/20846395
http://dx.doi.org/10.1186/1743-422X-7-237

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2949839/
https://www.ncbi.nlm.nih.gov/pubmed/20846395
http://dx.doi.org/10.1186/1743-422X-7-237

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