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The Δ4-desaturation pathway for DHA biosynthesis is operative in the human species: Differences between normal controls and children with the Zellweger syndrome

BACKGROUND: Docosahexaenoic acid (DHA, 22:6ω3) is a fundamental component of cell membranes, especially in the brain and retina. In the experimental animal, DHA deficiency leads to suboptimal neurological performance and visual deficiencies. Children with the Zellweger syndrome (ZS) have a profound...

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Detalles Bibliográficos
Autores principales: Martinez, Manuela, Ichaso, Natalia, Setien, Fernando, Durany, Nuria, Qiu, Xiao, Roesler, William
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2949860/
https://www.ncbi.nlm.nih.gov/pubmed/20828389
http://dx.doi.org/10.1186/1476-511X-9-98