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Filtering, FDR and power
BACKGROUND: In high-dimensional data analysis such as differential gene expression analysis, people often use filtering methods like fold-change or variance filters in an attempt to reduce the multiple testing penalty and improve power. However, filtering may introduce a bias on the multiple testing...
Autores principales: | , , |
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Formato: | Texto |
Lenguaje: | English |
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BioMed Central
2010
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2949886/ https://www.ncbi.nlm.nih.gov/pubmed/20822518 http://dx.doi.org/10.1186/1471-2105-11-450 |