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Sigma-2: Multiple sequence alignment of non-coding DNA via an evolutionary model
BACKGROUND: While most multiple sequence alignment programs expect that all or most of their input is known to be homologous, and penalise insertions and deletions, this is not a reasonable assumption for non-coding DNA, which is much less strongly conserved than protein-coding genes. Arguing that t...
Autores principales: | , |
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Formato: | Texto |
Lenguaje: | English |
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BioMed Central
2010
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2949893/ https://www.ncbi.nlm.nih.gov/pubmed/20846408 http://dx.doi.org/10.1186/1471-2105-11-464 |