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A virtual cycle: theory and experiment converge on the exit from mitosis
The cell division cycle can be modelled as a series of quantitative thresholds of cyclin-dependent kinase (CDK) activity. DNA synthesis has a lower threshold requirement for CDK than does entry into mitosis, and mitotic exit and re-setting of replication origins occur upon collapse of CDK activity b...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Faculty of 1000 Ltd
2010
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2950025/ https://www.ncbi.nlm.nih.gov/pubmed/20948801 http://dx.doi.org/10.3410/B2-33 |