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Glucokinase activators (GKAs) promise a new pharmacotherapy for diabetics

The glucose-phosphorylating enzyme glucokinase, a promising target for developing new antidiabetic agents, was identified through the combined efforts of basic research and human biochemical genetics. Allosteric glucokinase activators (GKAs) were discovered by high-throughput screening of a large co...

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Detalles Bibliográficos
Autores principales: Matschinsky, Franz M, Porte, Daniel
Formato: Texto
Lenguaje:English
Publicado: Medicine Reports Ltd 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2950051/
https://www.ncbi.nlm.nih.gov/pubmed/20948841
http://dx.doi.org/10.3410/M2-43