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Modeling genome-wide replication kinetics reveals a mechanism for regulation of replication timing

Microarrays are powerful tools to probe genome-wide replication kinetics. The rich data sets that result contain more information than has been extracted by current methods of analysis. In this paper, we present an analytical model that incorporates probabilistic initiation of origins and passive re...

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Detalles Bibliográficos
Autores principales: Yang, Scott Cheng-Hsin, Rhind, Nicholas, Bechhoefer, John
Formato: Texto
Lenguaje:English
Publicado: European Molecular Biology Organization 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2950085/
https://www.ncbi.nlm.nih.gov/pubmed/20739926
http://dx.doi.org/10.1038/msb.2010.61