Endoplasmic Reticulum Calcium Regulates the Retrotranslocation of Trypanosoma Cruzi Calreticulin to the Cytosol

For most secretory pathway proteins, crossing the endoplasmic reticulum (ER) membrane is an irreversible process. However, in some cases this flow can be reversed. For instance, misfolded proteins retained in the ER are retrotranslocated to the cytosol to be degraded by the proteasome. This mechanis...

Descripción completa

Detalles Bibliográficos
Autores principales: Labriola, Carlos A., Conte, Ianina L., López Medus, Máximo, Parodi, Armando J., Caramelo, Julio J.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2950133/
https://www.ncbi.nlm.nih.gov/pubmed/20957192
http://dx.doi.org/10.1371/journal.pone.0013141

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2950133/
https://www.ncbi.nlm.nih.gov/pubmed/20957192
http://dx.doi.org/10.1371/journal.pone.0013141

Ejemplares similares