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Endoplasmic Reticulum Calcium Regulates the Retrotranslocation of Trypanosoma Cruzi Calreticulin to the Cytosol

For most secretory pathway proteins, crossing the endoplasmic reticulum (ER) membrane is an irreversible process. However, in some cases this flow can be reversed. For instance, misfolded proteins retained in the ER are retrotranslocated to the cytosol to be degraded by the proteasome. This mechanis...

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Detalles Bibliográficos
Autores principales:	Labriola, Carlos A., Conte, Ianina L., López Medus, Máximo, Parodi, Armando J., Caramelo, Julio J.
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2010
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2950133/ https://www.ncbi.nlm.nih.gov/pubmed/20957192 http://dx.doi.org/10.1371/journal.pone.0013141

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