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Zip4 (Slc39a4) Expression is Activated in Hepatocellular Carcinomas and Functions to Repress Apoptosis, Enhance Cell Cycle and Increase Migration

BACKGROUND: The zinc transporter ZIP4 (Slc39a4) is important for proper mammalian development and is an essential gene in mice. Recent studies suggest that this gene may also play a role in pancreatic cancer. METHODS/PRINCIPAL FINDINGS: Herein, we present evidence that this essential zinc transporte...

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Detalles Bibliográficos
Autores principales: Weaver, Benjamin P., Zhang, Yuxia, Hiscox, Stephen, Guo, Grace L., Apte, Udayan, Taylor, Kathryn M., Sheline, Christian T., Wang, Li, Andrews, Glen K.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2950147/
https://www.ncbi.nlm.nih.gov/pubmed/20957146
http://dx.doi.org/10.1371/journal.pone.0013158