Cargando…
Zip4 (Slc39a4) Expression is Activated in Hepatocellular Carcinomas and Functions to Repress Apoptosis, Enhance Cell Cycle and Increase Migration
BACKGROUND: The zinc transporter ZIP4 (Slc39a4) is important for proper mammalian development and is an essential gene in mice. Recent studies suggest that this gene may also play a role in pancreatic cancer. METHODS/PRINCIPAL FINDINGS: Herein, we present evidence that this essential zinc transporte...
Autores principales: | Weaver, Benjamin P., Zhang, Yuxia, Hiscox, Stephen, Guo, Grace L., Apte, Udayan, Taylor, Kathryn M., Sheline, Christian T., Wang, Li, Andrews, Glen K. |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2010
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2950147/ https://www.ncbi.nlm.nih.gov/pubmed/20957146 http://dx.doi.org/10.1371/journal.pone.0013158 |
Ejemplares similares
-
Regulation of zinc-responsive Slc39a5 (Zip5) translation is mediated by conserved elements in the 3′-untranslated region
por: Weaver, Benjamin P., et al.
Publicado: (2011) -
A Mouse Model of Acrodermatitis Enteropathica: Loss of Intestine Zinc Transporter ZIP4 (Slc39a4) Disrupts the Stem Cell Niche and Intestine Integrity
por: Geiser, Jim, et al.
Publicado: (2012) -
Extreme Population Differences in the Human Zinc Transporter ZIP4 (SLC39A4) Are Explained by Positive Selection in Sub-Saharan Africa
por: Engelken, Johannes, et al.
Publicado: (2014) -
The Zinc Transporter Zip5 (Slc39a5) Regulates Intestinal Zinc Excretion and Protects the Pancreas against Zinc Toxicity
por: Geiser, Jim, et al.
Publicado: (2013) -
Recent Advances in the Role of SLC39A/ZIP Zinc Transporters In Vivo
por: Takagishi, Teruhisa, et al.
Publicado: (2017)