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Adaptive Evolution of the Chlamydia trachomatis Dominant Antigen Reveals Distinct Evolutionary Scenarios for B- and T-cell Epitopes: Worldwide Survey

BACKGROUND: Chlamydia trachomatis is one of the most disseminated human pathogens, for which no vaccine is available yet. Understanding the impact of the host pressure on pathogen antigens is crucial, but so far it was only assessed for highly-restricted geographic areas. We aimed to evaluate the ev...

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Detalles Bibliográficos
Autores principales: Nunes, Alexandra, Nogueira, Paulo J., Borrego, Maria J., Gomes, João P.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2950151/
https://www.ncbi.nlm.nih.gov/pubmed/20957150
http://dx.doi.org/10.1371/journal.pone.0013171