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Human Fatal Zaire Ebola Virus Infection Is Associated with an Aberrant Innate Immunity and with Massive Lymphocyte Apoptosis

BACKGROUND: Ebolavirus species Zaire (ZEBOV) causes highly lethal hemorrhagic fever, resulting in the death of 90% of patients within days. Most information on immune responses to ZEBOV comes from in vitro studies and animal models. The paucity of data on human immune responses to this virus is main...

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Detalles Bibliográficos
Autores principales: Wauquier, Nadia, Becquart, Pierre, Padilla, Cindy, Baize, Sylvain, Leroy, Eric M.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2950153/
https://www.ncbi.nlm.nih.gov/pubmed/20957152
http://dx.doi.org/10.1371/journal.pntd.0000837