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Profiling of Substrate Specificity of SARS-CoV 3CL(pro)

BACKGROUND: The 3C-like protease (3CL(pro)) of severe acute respiratory syndrome-coronavirus is required for autoprocessing of the polyprotein, and is a potential target for treating coronaviral infection. METHODOLOGY/PRINCIPAL FINDINGS: To obtain a thorough understanding of substrate specificity of...

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Detalles Bibliográficos
Autores principales: Chuck, Chi-Pang, Chong, Lin-Tat, Chen, Chao, Chow, Hak-Fun, Wan, David Chi-Cheong, Wong, Kam-Bo
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2950840/
https://www.ncbi.nlm.nih.gov/pubmed/20949131
http://dx.doi.org/10.1371/journal.pone.0013197