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Correlation Analysis for Protein Evolutionary Family Based on Amino Acid Position Mutations and Application in PDZ Domain

BACKGROUND: It has been widely recognized that the mutations at specific directions are caused by the functional constraints in protein family and the directional mutations at certain positions control the evolutionary direction of the protein family. The mutations at different positions, even dista...

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Detalles Bibliográficos
Autores principales: Du, Qi-Shi, Wang, Cheng-Hua, Liao, Si-Ming, Huang, Ri-Bo
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2950854/
https://www.ncbi.nlm.nih.gov/pubmed/20949088
http://dx.doi.org/10.1371/journal.pone.0013207