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In Vivo Islet Protection by a Nuclear Import Inhibitor in a Mouse Model of Type 1 Diabetes

BACKGROUND: Insulin-dependent Type 1 diabetes (T1D) is a devastating autoimmune disease that destroys beta cells within the pancreatic islets and afflicts over 10 million people worldwide. These patients face life-long risks for blindness, cardiovascular and renal diseases, and complications of insu...

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Detalles Bibliográficos
Autores principales: Moore, Daniel J., Zienkiewicz, Jozef, Kendall, Peggy L., Liu, Danya, Liu, Xueyan, Veach, Ruth Ann, Collins, Robert D., Hawiger, Jacek
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2950856/
https://www.ncbi.nlm.nih.gov/pubmed/20949090
http://dx.doi.org/10.1371/journal.pone.0013235