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E. coli RecBC Helicase has Two Translocase Activities Controlled by a Single ATPase Motor

Escherichia coli RecBCD is a DNA helicase with two ATPase motors (RecB, a 3′ to 5′ translocase, and RecD, a 5′ to 3′ translocase) that functions in repair of double-stranded DNA breaks. The RecBC heterodimer, with only the RecB motor, remains a processive helicase. Here we examined RecBC translocati...

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Detalles Bibliográficos
Autores principales: Wu, Colin G., Bradford, Christina, Lohman, Timothy M.
Formato: Texto
Lenguaje:English
Publicado: 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2950890/
https://www.ncbi.nlm.nih.gov/pubmed/20852646
http://dx.doi.org/10.1038/nsmb.1901