Enhancement of the RAD51 Recombinase Activity by the Tumor Suppressor PALB2

Homologous recombination mediated by the RAD51 recombinase helps eliminate chromosomal lesions, such as DNA double-stranded breaks induced by radiation or arising from injured DNA replication forks. The tumor suppressors BRCA2 and PALB2 act together to deliver RAD51 to chromosomal lesions to initiat...

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Detalles Bibliográficos
Autores principales: Dray, Eloïse, Etchin, Julia, Wiese, Claudia, Saro, Dorina, Williams, Gareth J., Hammel, Michal, Yu, Xiong, Galkin, Vitold E., Liu, Dongqing, Tsai, Miaw-Sheue, Sy, Shirley M-H., Schild, David, Egelman, Edward, Chen, Junjie, Sung, Patrick
Formato: Texto
Lenguaje:English
Publicado: 2010
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2950913/
https://www.ncbi.nlm.nih.gov/pubmed/20871616
http://dx.doi.org/10.1038/nsmb.1916

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2950913/
https://www.ncbi.nlm.nih.gov/pubmed/20871616
http://dx.doi.org/10.1038/nsmb.1916

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