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A Gibbs sampling strategy applied to the mapping of ambiguous short-sequence tags
Motivation: Chromatin immunoprecipitation followed by high-throughput sequencing (ChIP-seq) is widely used in biological research. ChIP-seq experiments yield many ambiguous tags that can be mapped with equal probability to multiple genomic sites. Such ambiguous tags are typically eliminated from con...
Autores principales: | , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2951085/ https://www.ncbi.nlm.nih.gov/pubmed/20871106 http://dx.doi.org/10.1093/bioinformatics/btq460 |