Cargando…

A Gibbs sampling strategy applied to the mapping of ambiguous short-sequence tags

Motivation: Chromatin immunoprecipitation followed by high-throughput sequencing (ChIP-seq) is widely used in biological research. ChIP-seq experiments yield many ambiguous tags that can be mapped with equal probability to multiple genomic sites. Such ambiguous tags are typically eliminated from con...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Jianrong, Huda, Ahsan, Lunyak, Victoria V., Jordan, I. King
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2951085/
https://www.ncbi.nlm.nih.gov/pubmed/20871106
http://dx.doi.org/10.1093/bioinformatics/btq460