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A Gibbs sampling strategy applied to the mapping of ambiguous short-sequence tags

Motivation: Chromatin immunoprecipitation followed by high-throughput sequencing (ChIP-seq) is widely used in biological research. ChIP-seq experiments yield many ambiguous tags that can be mapped with equal probability to multiple genomic sites. Such ambiguous tags are typically eliminated from con...

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Detalles Bibliográficos
Autores principales: Wang, Jianrong, Huda, Ahsan, Lunyak, Victoria V., Jordan, I. King
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2951085/
https://www.ncbi.nlm.nih.gov/pubmed/20871106
http://dx.doi.org/10.1093/bioinformatics/btq460

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