Cargando…

Expression of Rod-Derived Cone Viability Factor: Dual Role of CRX in Regulating Promoter Activity and Cell-Type Specificity

BACKGROUND: RdCVF and RdCVF2, encoded by the nucleoredoxin-like genes NXNL1 and NXNL2, are trophic factors with therapeutic potential that are involved in cone photoreceptor survival. Studying how their expression is regulated in the retina has implications for understanding both their activity and...

Descripción completa

Detalles Bibliográficos
Autores principales: Lambard, Sophie, Reichman, Sacha, Berlinicke, Cynthia, Niepon, Marie-Laure, Goureau, Olivier, Sahel, José-Alain, Léveillard, Thierry, Zack, Donald J.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2951342/
https://www.ncbi.nlm.nih.gov/pubmed/20949100
http://dx.doi.org/10.1371/journal.pone.0013075