Loss of LMO4 in the Retina Leads to Reduction of GABAergic Amacrine Cells and Functional Deficits

BACKGROUND: LMO4 is a transcription cofactor expressed during retinal development and in amacrine neurons at birth. A previous study in zebrafish reported that morpholino RNA ablation of one of two related genes, LMO4b, increases the size of eyes in embryos. However, the significance of LMO4 in mamm...

Descripción completa

Detalles Bibliográficos
Autores principales: Duquette, Philippe M., Zhou, Xun, Yap, Nida Lerma, MacLaren, Erik J., Lu, Jesse J., Wallace, Valerie A., Chen, Hsiao-Huei
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2951357/
https://www.ncbi.nlm.nih.gov/pubmed/20949055
http://dx.doi.org/10.1371/journal.pone.0013232

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2951357/
https://www.ncbi.nlm.nih.gov/pubmed/20949055
http://dx.doi.org/10.1371/journal.pone.0013232

Ejemplares similares