Inhibition of Plasmodium falciparum Field Isolates-Mediated Endothelial Cell Apoptosis by Fasudil: Therapeutic Implications for Severe Malaria

Plasmodium falciparum infection can abruptly progress to severe malaria, a life-threatening complication resulting from sequestration of parasitized red blood cells (PRBC) in the microvasculature of various organs such as the brain and lungs. PRBC adhesion can induce endothelial cell (EC) activation...

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Detalles Bibliográficos
Autores principales: Zang-Edou, Estelle S., Bisvigou, Ulrick, Taoufiq, Zacharie, Lékoulou, Faustin, Lékana-Douki, Jean Bernard, Traoré, Yves, Mazier, Dominique, Touré-Ndouo, Fousseyni S.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2951358/
https://www.ncbi.nlm.nih.gov/pubmed/20949056
http://dx.doi.org/10.1371/journal.pone.0013221

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2951358/
https://www.ncbi.nlm.nih.gov/pubmed/20949056
http://dx.doi.org/10.1371/journal.pone.0013221

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