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Crystal Structure of Legionella DotD: Insights into the Relationship between Type IVB and Type II/III Secretion Systems
The Dot/Icm type IVB secretion system (T4BSS) is a pivotal determinant of Legionella pneumophila pathogenesis. L. pneumophila translocate more than 100 effector proteins into host cytoplasm using Dot/Icm T4BSS, modulating host cellular functions to establish a replicative niche within host cells. Th...
Autores principales: | , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2951367/ https://www.ncbi.nlm.nih.gov/pubmed/20949065 http://dx.doi.org/10.1371/journal.ppat.1001129 |