Viral Replication Rate Regulates Clinical Outcome and CD8 T Cell Responses during Highly Pathogenic H5N1 Influenza Virus Infection in Mice

Since the first recorded infection of humans with H5N1 viruses of avian origin in 1997, sporadic human infections continue to occur with a staggering mortality rate of >60%. Although sustained human-to-human transmission has not occurred yet, there is a growing concern that these H5N1 viruses mig...

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Detalles Bibliográficos
Autores principales: Hatta, Yasuko, Hershberger, Karen, Shinya, Kyoko, Proll, Sean C., Dubielzig, Richard R., Hatta, Masato, Katze, Michael G., Kawaoka, Yoshihiro, Suresh, M.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2951384/
https://www.ncbi.nlm.nih.gov/pubmed/20949022
http://dx.doi.org/10.1371/journal.ppat.1001139

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2951384/
https://www.ncbi.nlm.nih.gov/pubmed/20949022
http://dx.doi.org/10.1371/journal.ppat.1001139

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