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Low thymine content in PINK1 mRNAs and insights into Parkinson’s disease

Thymine is the only nucleotide base which is changed to uracil upon transcription, leaving mRNA less hydrophobic compared to its DNA counterpart. All the 16 codons that contain uracil (or thymine in gene) as the second nucleotide code for the five large hydrophobic residues (LHRs), namely phenylalan...

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Detalles Bibliográficos
Autores principales: Anandagopu, Perumal, Banu, Shamima, Li, Jinyan
Formato: Texto
Lenguaje:English
Publicado: Biomedical Informatics Publishing Group 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2951701/
https://www.ncbi.nlm.nih.gov/pubmed/20975909