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Interaction of CTX­M­15 enzyme with cefotaxime: a molecular modelling and docking study

1. Modelling of CTX­M enzyme from bla(CTX­M) sequences of clinical Escherichia coli isolates. 2. Docking of cefotaxime with modelled CTX­M enzymes to identify amino acid residues crucial to their interaction . 3. To hypothesize a possible relationship between ’interaction energy of the docked enzyme...

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Detalles Bibliográficos
Autores principales: Shakil, Shazi, Khan, Asad Ullah
Formato: Texto
Lenguaje:English
Publicado: Biomedical Informatics Publishing Group 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2951708/
https://www.ncbi.nlm.nih.gov/pubmed/20975911