αB Crystallin Is Apically Secreted within Exosomes by Polarized Human Retinal Pigment Epithelium and Provides Neuroprotection to Adjacent Cells

αB Crystallin is a chaperone protein with anti-apoptotic and anti-inflammatory functions and has been identified as a biomarker in age-related macular degeneration. The purpose of this study was to determine whether αB crystallin is secreted from retinal pigment epithelial (RPE) cells, the mechanism...

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Detalles Bibliográficos
Autores principales: Sreekumar, Parameswaran G., Kannan, Ram, Kitamura, Mizuki, Spee, Christine, Barron, Ernesto, Ryan, Stephen J., Hinton, David R.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2951891/
https://www.ncbi.nlm.nih.gov/pubmed/20949024
http://dx.doi.org/10.1371/journal.pone.0012578

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2951891/
https://www.ncbi.nlm.nih.gov/pubmed/20949024
http://dx.doi.org/10.1371/journal.pone.0012578

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