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Deciphering the Structure, Growth and Assembly of Amyloid-Like Fibrils Using High-Speed Atomic Force Microscopy

Formation of fibrillar structures of proteins that deposit into aggregates has been suggested to play a key role in various neurodegenerative diseases. However mechanisms and dynamics of fibrillization remains to be elucidated. We have previously established that lithostathine, a protein overexpress...

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Detalles Bibliográficos
Autores principales: Milhiet, Pierre-Emmanuel, Yamamoto, Daisuke, Berthoumieu, Olivia, Dosset, Patrice, Le Grimellec, Christian, Verdier, Jean-Michel, Marchal, Stéphane, Ando, Toshio
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2951901/
https://www.ncbi.nlm.nih.gov/pubmed/20949034
http://dx.doi.org/10.1371/journal.pone.0013240