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Sss1p Is Required to Complete Protein Translocon Activation

Protein translocation across the endoplasmic reticulum membrane occurs at the Sec61 translocon. This has two essential subunits, the channel-forming multispanning membrane protein Sec61p/Sec61α and the tail-anchored Sss1p/Sec61γ, which has been proposed to “clamp” the channel. We have analyzed the f...

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Detalles Bibliográficos
Autores principales: Wilkinson, Barrie M., Brownsword, Judith K., Mousley, Carl J., Stirling, Colin J.
Formato: Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2952269/
https://www.ncbi.nlm.nih.gov/pubmed/20709746
http://dx.doi.org/10.1074/jbc.M110.128256