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New class of agents for treatment of hypertension: focus on direct renin inhibition

Aliskiren, the first orally active direct renin inhibitor, is an effective antihypertensive drug with distinctive characteristics, including good blockade of the renin-angiotensin system, a prolonged duration of action, pharmacologic effects that persist after drug discontinuation, and favorable tol...

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Detalles Bibliográficos
Autores principales: Fogari, Roberto, Zoppi, Annalisa
Formato: Texto
Lenguaje:English
Publicado: Dove Medical Press 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2952455/
https://www.ncbi.nlm.nih.gov/pubmed/20957132
http://dx.doi.org/10.2147/VHRM.S4189