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New class of agents for treatment of hypertension: focus on direct renin inhibition
Aliskiren, the first orally active direct renin inhibitor, is an effective antihypertensive drug with distinctive characteristics, including good blockade of the renin-angiotensin system, a prolonged duration of action, pharmacologic effects that persist after drug discontinuation, and favorable tol...
Autores principales: | , |
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Formato: | Texto |
Lenguaje: | English |
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Dove Medical Press
2010
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2952455/ https://www.ncbi.nlm.nih.gov/pubmed/20957132 http://dx.doi.org/10.2147/VHRM.S4189 |