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Consecutive pharmacological activation of PKA and PKC mimics the potent cardioprotection of temperature preconditioning

AIMS: Temperature preconditioning (TP) provides very powerful protection against ischaemia/reperfusion. Understanding the signalling pathways involved may enable the development of effective pharmacological cardioprotection. We investigated the interrelationship between activation of protein kinase...

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Detalles Bibliográficos
Autores principales: Khaliulin, Igor, Parker, Joanna E., Halestrap, Andrew P.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2952531/
https://www.ncbi.nlm.nih.gov/pubmed/20558443
http://dx.doi.org/10.1093/cvr/cvq190