Down's syndrome-like cardiac developmental defects in embryos of the transchromosomic Tc1 mouse

AIMS: Cardiac malformations are prevalent in trisomies of human chromosome 21 [Down's syndrome (DS)], affecting normal chamber separation in the developing heart. Efforts to understand the aetiology of these defects have been severely hampered by the absence of an accurate mouse model. Such mod...

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Detalles Bibliográficos
Autores principales: Dunlevy, Louisa, Bennett, Mike, Slender, Amy, Lana-Elola, Eva, Tybulewicz, Victor L., Fisher, Elizabeth M.C., Mohun, Timothy
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2010
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2952533/
https://www.ncbi.nlm.nih.gov/pubmed/20558441
http://dx.doi.org/10.1093/cvr/cvq193

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2952533/
https://www.ncbi.nlm.nih.gov/pubmed/20558441
http://dx.doi.org/10.1093/cvr/cvq193

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