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Down's syndrome-like cardiac developmental defects in embryos of the transchromosomic Tc1 mouse
AIMS: Cardiac malformations are prevalent in trisomies of human chromosome 21 [Down's syndrome (DS)], affecting normal chamber separation in the developing heart. Efforts to understand the aetiology of these defects have been severely hampered by the absence of an accurate mouse model. Such mod...
| Autores principales: | , , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2010
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2952533/ https://www.ncbi.nlm.nih.gov/pubmed/20558441 http://dx.doi.org/10.1093/cvr/cvq193 |