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Insights on Glucocorticoid Receptor Activity Modulation through the Binding of Rigid Steroids
BACKGROUND: The glucocorticoid receptor (GR) is a transcription factor that regulates gene expression in a ligand-dependent fashion. This modular protein is one of the major pharmacological targets due to its involvement in both cause and treatment of many human diseases. Intense efforts have been m...
| Autores principales: | , , , , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2010
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2952596/ https://www.ncbi.nlm.nih.gov/pubmed/20949009 http://dx.doi.org/10.1371/journal.pone.0013279 |