Insights on Glucocorticoid Receptor Activity Modulation through the Binding of Rigid Steroids
BACKGROUND: The glucocorticoid receptor (GR) is a transcription factor that regulates gene expression in a ligand-dependent fashion. This modular protein is one of the major pharmacological targets due to its involvement in both cause and treatment of many human diseases. Intense efforts have been m...
Autores principales: | , , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2952596/ https://www.ncbi.nlm.nih.gov/pubmed/20949009 http://dx.doi.org/10.1371/journal.pone.0013279 |