Live Cell Imaging Unveils Multiple Domain Requirements for In Vivo Dimerization of the Glucocorticoid Receptor

Glucocorticoids are essential for life, but are also implicated in disease pathogenesis and may produce unwanted effects when given in high doses. Glucocorticoid receptor (GR) transcriptional activity and clinical outcome have been linked to its oligomerization state. Although a point mutation withi...

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Detalles Bibliográficos
Autores principales: Presman, Diego M., Ogara, M. Florencia, Stortz, Martín, Alvarez, Lautaro D., Pooley, John R., Schiltz, R. Louis, Grøntved, Lars, Johnson, Thomas A., Mittelstadt, Paul R., Ashwell, Jonathan D., Ganesan, Sundar, Burton, Gerardo, Levi, Valeria, Hager, Gordon L., Pecci, Adali
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3958349/
https://www.ncbi.nlm.nih.gov/pubmed/24642507
http://dx.doi.org/10.1371/journal.pbio.1001813

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3958349/
https://www.ncbi.nlm.nih.gov/pubmed/24642507
http://dx.doi.org/10.1371/journal.pbio.1001813

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