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Genome-Wide Data-Mining of Candidate Human Splice Translational Efficiency Polymorphisms (STEPs) and an Online Database
BACKGROUND: Variation in pre-mRNA splicing is common and in some cases caused by genetic variants in intronic splicing motifs. Recent studies into the insulin gene (INS) discovered a polymorphism in a 5′ non-coding intron that influences the likelihood of intron retention in the final mRNA, extendin...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2010
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2952627/ https://www.ncbi.nlm.nih.gov/pubmed/20948966 http://dx.doi.org/10.1371/journal.pone.0013340 |