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Mesenchymal Stem Cells and the Origin of Ewing's Sarcoma

The origin of Ewing's sarcoma is a subject of much debate. Once thought to be derived from primitive neuroectodermal cells, many now believe it to arise from a mesenchymal stem cell (MSC). Expression of the EWS-FLI1 fusion gene in MSCs changes cell morphology to resemble Ewing's sarcoma an...

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Detalles Bibliográficos
Autores principales: Lin, Patrick P., Wang, Yongxing, Lozano, Guillermina
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2952797/
https://www.ncbi.nlm.nih.gov/pubmed/20953407
http://dx.doi.org/10.1155/2011/276463