Bioassay-Guided Evaluation of Antinociceptive Effect of N-Salicyloyltryptamine: A Behavioral and Electrophysiological Approach

We investigated the antinociceptive and nerve excitability effects of the N-salicyloyltryptamine (NST) NST-treated mice exhibited a significant decrease in the number of writhes when 100 and 200 mg/kg (i.p.) were administered (i.p.). This effect was not antagonized by naloxone (1.5 mg/kg, i.p.). NST...

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Detalles Bibliográficos
Autores principales: Quintans-Júnior, Lucindo J., Silva, Davi A., Siqueira, Jullyana S., Araújo, Adriano A. S., Barreto, Rosana S. S., Bonjardim, Leonardo R., DeSantana, Josimari M., De Lucca Júnior, Waldeci, Souza, Maria F. V., Gutierrez, Stanley J. C., Barbosa-Filho, José Maria, Santana-Filho, Valter J., Araújo, Demétrius A. M., Almeida, Reinaldo N.
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2952823/
https://www.ncbi.nlm.nih.gov/pubmed/20976310
http://dx.doi.org/10.1155/2010/230745

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2952823/
https://www.ncbi.nlm.nih.gov/pubmed/20976310
http://dx.doi.org/10.1155/2010/230745

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