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Bioassay-Guided Evaluation of Antinociceptive Effect of N-Salicyloyltryptamine: A Behavioral and Electrophysiological Approach
We investigated the antinociceptive and nerve excitability effects of the N-salicyloyltryptamine (NST) NST-treated mice exhibited a significant decrease in the number of writhes when 100 and 200 mg/kg (i.p.) were administered (i.p.). This effect was not antagonized by naloxone (1.5 mg/kg, i.p.). NST...
Autores principales: | Quintans-Júnior, Lucindo J., Silva, Davi A., Siqueira, Jullyana S., Araújo, Adriano A. S., Barreto, Rosana S. S., Bonjardim, Leonardo R., DeSantana, Josimari M., De Lucca Júnior, Waldeci, Souza, Maria F. V., Gutierrez, Stanley J. C., Barbosa-Filho, José Maria, Santana-Filho, Valter J., Araújo, Demétrius A. M., Almeida, Reinaldo N. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2952823/ https://www.ncbi.nlm.nih.gov/pubmed/20976310 http://dx.doi.org/10.1155/2010/230745 |
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