Runx1 binds as a dimeric complex to overlapping Runx1 sites within a palindromic element in the human GM-CSF enhancer

Runx1 is a developmentally regulated transcription factor that is essential for haemopoiesis. Runx1 can bind as a monomer to the core consensus sequence TGTGG, but binds more efficiently as a hetero-dimer together with the non-DNA binding protein CBFβ as a complex termed core binding factor (CBF). H...

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Detalles Bibliográficos
Autores principales: Bowers, Sarion R., Calero-Nieto, Fernando J., Valeaux, Stephanie, Fernandez-Fuentes, Narcis, Cockerill, Peter N.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2010
Materias:
Molecular Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2952845/
https://www.ncbi.nlm.nih.gov/pubmed/20483917
http://dx.doi.org/10.1093/nar/gkq356

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2952845/
https://www.ncbi.nlm.nih.gov/pubmed/20483917
http://dx.doi.org/10.1093/nar/gkq356

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