Insights into the hyperthermostability and unusual region-specificity of archaeal Pyrococcus abyssi tRNA m(1)A57/58 methyltransferase

The S-adenosyl-l-methionine dependent methylation of adenine 58 in the T-loop of tRNAs is essential for cell growth in yeast or for adaptation to high temperatures in thermophilic organisms. In contrast to bacterial and eukaryotic tRNA m(1)A58 methyltransferases that are site-specific, the homologou...

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Detalles Bibliográficos
Autores principales: Guelorget, Amandine, Roovers, Martine, Guérineau, Vincent, Barbey, Carole, Li, Xuan, Golinelli-Pimpaneau, Béatrice
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2010
Materias:
Nucleic Acid Enzymes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2952851/
https://www.ncbi.nlm.nih.gov/pubmed/20483913
http://dx.doi.org/10.1093/nar/gkq381

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2952851/
https://www.ncbi.nlm.nih.gov/pubmed/20483913
http://dx.doi.org/10.1093/nar/gkq381

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