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Insights into the hyperthermostability and unusual region-specificity of archaeal Pyrococcus abyssi tRNA m(1)A57/58 methyltransferase
The S-adenosyl-l-methionine dependent methylation of adenine 58 in the T-loop of tRNAs is essential for cell growth in yeast or for adaptation to high temperatures in thermophilic organisms. In contrast to bacterial and eukaryotic tRNA m(1)A58 methyltransferases that are site-specific, the homologou...
| Autores principales: | , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2010
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2952851/ https://www.ncbi.nlm.nih.gov/pubmed/20483913 http://dx.doi.org/10.1093/nar/gkq381 |