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Functional analysis and identification of cis-regulatory elements of human chromosome 21 gene promoters

Given the inherent limitations of in silico studies relying solely on DNA sequence analysis, the functional characterization of mammalian promoters and associated cis-regulatory elements requires experimental support, which demands cloning and analysis of putative promoter regions. Focusing on human...

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Detalles Bibliográficos
Autores principales: Warnatz, Hans-Jörg, Querfurth, Robert, Guerasimova, Anna, Cheng, Xi, Haas, Stefan A., Hufton, Andrew L., Manke, Thomas, Vanhecke, Dominique, Nietfeld, Wilfried, Vingron, Martin, Janitz, Michal, Lehrach, Hans, Yaspo, Marie-Laure
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2952857/
https://www.ncbi.nlm.nih.gov/pubmed/20494980
http://dx.doi.org/10.1093/nar/gkq402