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Perturbations in nucleosome structure from heavy metal association

Heavy metals have the potential to engage in strong bonding interactions and can thus function in essential as well as toxic or therapeutic capacities. We conducted crystallographic analyses of heavy cation binding to the nucleosome core particle and found that Co(2+) and Ni(2+) preferentially assoc...

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Detalles Bibliográficos
Autores principales: Mohideen, Kareem, Muhammad, Reyhan, Davey, Curt A.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2952864/
https://www.ncbi.nlm.nih.gov/pubmed/20494975
http://dx.doi.org/10.1093/nar/gkq420