Single molecule linear analysis of DNA in nano-channel labeled with sequence specific fluorescent probes

An array of nano-channels was fabricated from silicon based semiconductor materials to stretch long, native dsDNA. Here we present a labeling scheme in which it is possible to identify the location of specific sequences along the stretched DNA molecules. The scheme proceeds by first using the strand...

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Detalles Bibliográficos
Autores principales: Das, Somes K., Austin, Michael D., Akana, Matthew C., Deshpande, Paru, Cao, Han, Xiao, Ming
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2010
Materias:
Methods Online
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2952877/
https://www.ncbi.nlm.nih.gov/pubmed/20699272
http://dx.doi.org/10.1093/nar/gkq673

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2952877/
https://www.ncbi.nlm.nih.gov/pubmed/20699272
http://dx.doi.org/10.1093/nar/gkq673

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